diff --git a/backends/qualcomm/partition/qnn_partitioner.py b/backends/qualcomm/partition/qnn_partitioner.py
index 8db23a465ef..77f99ddd1d5 100644
--- a/backends/qualcomm/partition/qnn_partitioner.py
+++ b/backends/qualcomm/partition/qnn_partitioner.py
@@ -41,6 +41,7 @@
     PartitionResult,
 )
 from executorch.exir.backend.utils import tag_constant_data, tag_mutated_buffer
+from executorch.exir.dialects._ops import ops as exir_ops
 from torch.export.exported_program import ExportedProgram
 from torch.fx.passes.infra.partitioner import Partition
 from torch.fx.passes.operator_support import OperatorSupportBase
@@ -113,7 +114,7 @@ def __init__(
             for soc_model in target_socs
         ]
 
-    def is_node_supported(self, _, node: torch.fx.Node) -> bool:
+    def is_node_supported(self, _, node: torch.fx.Node) -> bool:  # noqa: C901
         if node.op != "call_function" or node.target in not_supported_operator:
             return False
 
@@ -168,6 +169,20 @@ def is_node_supported(self, _, node: torch.fx.Node) -> bool:
                 node, self.soc_info.htp_info.vtcm_size_in_mb, self.phase
             )
 
+        if node.target in constant_operator:
+            # Built as a static tensor, so every value it depends on must be known AoT
+            # (full_like's first argument only supplies the shape).
+            shape_only = (
+                node.args[0]
+                if node.target == exir_ops.edge.aten.full_like.default
+                else None
+            )
+            if any(arg is not shape_only for arg in node.all_input_nodes):
+                logger.info(
+                    f"[{self.phase}] {node.target.__name__} | Skipped, value is only known at runtime"
+                )
+                return False
+
         supported = False
         if node.target.__name__ not in self.node_visitors:
             logger.info(
diff --git a/backends/qualcomm/tests/test_passes.py b/backends/qualcomm/tests/test_passes.py
index 606fed01d72..2fb17f6f6e1 100644
--- a/backends/qualcomm/tests/test_passes.py
+++ b/backends/qualcomm/tests/test_passes.py
@@ -783,6 +783,42 @@ def forward(self, x):
             if "QNN" in str(e) or "qnn" in str(e):
                 self.skipTest(f"QNN SDK not available: {e}")
 
+    def test_full_with_runtime_fill_value_stays_on_cpu(self):
+        """aten.full is lowered as a static tensor, so a fill_value only known at runtime
+        (YOLO's `torch.full(..., stride.item())`) must leave it on CPU rather than crash
+        the partitioner's support check.
+        """
+
+        class FullFromTensor(torch.nn.Module):
+            def __init__(self):
+                super().__init__()
+                self.register_buffer("stride", torch.tensor([8.0, 16.0]))
+
+            def forward(self, x):
+                return x * torch.full((4, 1), self.stride[0].item())
+
+        sample_input = (torch.randn(4, 3),)
+        compiler_specs = generate_qnn_executorch_compiler_spec(
+            soc_model=QcomChipset.SM8650,
+            backend_options=generate_htp_compiler_spec(use_fp16=True),
+        )
+        try:
+            edge = to_edge_transform_and_lower_to_qnn(
+                FullFromTensor(), sample_input, compiler_specs
+            )
+        except RuntimeError as e:
+            if "QNN" in str(e) or "qnn" in str(e):
+                self.skipTest(f"QNN SDK not available: {e}")
+            raise
+
+        self.assertTrue(
+            any(
+                node.op == "call_function" and "aten.full" in str(node.target)
+                for node in edge.exported_program().graph.nodes
+            )
+        )
+        edge.to_executorch()
+
     def test_lowering_accepts_exported_program_without_reexport(self):
         """to_edge_transform_and_lower_to_qnn must lower a caller-supplied
         ExportedProgram as captured, never re-exporting it.